I've only tripped up on a couple of the campaign adventures, one because I am an all dwarf party, and just not geared for lots of rapid movement to get to the duke in the back corner hiding behind his dogs. That was a very tough one to get past. The other one is the puddings/skeletons final battle. The skeletons almost always seem to have the card that stops all damage from slicing weapons, and then the puddings have armor that always nullfies crushing damage...two of your three players are melee weapons and it's rather difficult to get the cards when needed. Also, the generally open layout of the map guarantees that pretty much you were getting nailed by all 5 monsters every round. The group move cards ensured that even though they were slow monsters, they would be on your party within 2 turns. I ended up having to hide in the entry corner, to limit their access as much as I could, throw the 4 points of fire damage to everyone card twice, and try to stack the deck for armor melting/memory loss cards to get rid of one or both armors. Exceptionally challenging final battle. If I didn't get exactly the right draw, there was just no fending off the damage/dealing enough before their health boosting and armor rendered my damage output ineffective. I did get past it, but it was certainly more of a grind than a challenge.