Most cards which care about adjacency are broken for large (2x2) figures, since the adjacency check looks only at neighbors to the bottom-right location of the large figure. Broken cards in large figure decks: Muscle Through Charge (1) Possibly broken cards not presently in large figure decks: Violent Spin Large Weapon Working cards in large figure decks: Mindless Battlerage all sweeps
What about the reverse? Does a muscle through or violent spin move a large figure if you're not adjacent to their bottom-right square?
This one happened by accident in MM5 stage one and went by too fast for me to be sure, but Arcing Spark I believe counts distance only to the "home square" of the 2x2 figures.